Read e-book online Advances in the Immunopathogenesis of Multiple Sclerosis PDF

By Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro

ISBN-10: 884700067X

ISBN-13: 9788847000674

P.A. MURARO, A. LUGARESI, D. GAMBI a number of the pathological elements of a number of sclerosis (MS) lesions were identified for over a century. it's only lately, notwithstanding, that diversified styles of demyelination were associated with specific pathways of immune-mediated tissue destruction. specifically, the inter-individual heterogeneity of MS lesions has prompt that diverse mechanisms could act in several sufferers, accounting for the range saw in medical direction, immunological findings in peripheral blood and cere­ brospinal fluid (CSF), and reaction to immunomodulatory remedies. to supply an outline of the elemental mechanisms probably interested by MS lesion initiation and improvement, a world assembly used to be equipped within the context of the yearly Congress of the Italian Neuroimmunology organization (AINI), held on the college of Chieti, in Chieti Italy on 29 October 1998. The excessive typical of displays triggered us to document them in prolonged shape, to focus on fresh professional­ gress within the knowing of easy mechanisms maintaining MS immuno­ pathogenesis. A significant function within the attainable mechanisms resulting in myelin destruc­ tion has been attributed to T lymphocytes reactive to myelin antigens. stories at the myelin antigen-specific T phone repertoire have contributed major advances to our wisdom of autoimmunity (Chapters 1,2).

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Advances in the Immunopathogenesis of Multiple Sclerosis by Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro

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